Focus Areas in the Genomic Medicine Cycle
Major leadership positions

Director, MGH Center for Quantitative Health

MGH Department/Division



Our lab focuses on developing clinical and genomic predictors of treatment response, and on developing novel therapeutics based on cellular models of brain disease.

We use cellular modeling, transcriptomics, clinical phenotyping, and small molecule screening to study psychiatric disorders including schizophrenia, bipolar disorder, and depression. We aim to provide critical resources for the neurobiological community, with high-dimensionality data extending a fully annotated and shareable biobank of patient and healthy control cells.

Lab Members

Hana Yeh, PhDPostdoctoral Research Fellow
Laura Domenech Salgado, PhDPostdoctoral Research Fellow
Rose De Guzman, PhDPostdoctoral Research Fellow
Youngjung Rachel Jim, MD, PhDPsychiatrist
Primary Email

rperlis [@]

Lab Website